Can Lupus Affect Your Liver? Lupus also known as systemic lupus erythematosus (SLE), is an autoimmune disease that can affect various parts of the body. While most commonly associated with joint pain, skin rashes, and fatigue, lupus can also impact the liver. In this article, we will explore the relationship between lupus and the liver, examining the symptoms, causes, … [Read more...] about Can Lupus Affect Your Liver?